In 1982 Sergey Derugin graduated with honors from the Mogilev College of Construction and was awarded the Diploma in Industrial and Civil Engineering. After serving in the Soviet Army, he was employed as an engineer for capital repairs at the Mogilev Mechanical Engineering Institute.
In 1991 Sergey Derugin graduated from the Mogilev Machine-Building Institute with a degree in Hoisting-and-Transporting Machines and Equipment. For a long time he worked as a key specialist in the department responsible for maintenance and repair of University buildings and structures.
In 2016 he was appointed Acting Vice Rector for Administrative and Maintenance Work.